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Covetrus (#26080)

Zylkene® Equine Powder

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Feeding Chart

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Feeding Chart
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Inactive Dog - Less than 30 minutes of vigorous exercise daily
Active Dog - At least 30 minutes of vigorous exercise daily
Working Dog - More than two hours of vigorous exercise daily
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Product Overview

Temperament Support for Stressful Situations

Zylkene Equine is a unique calming supplement that contains alpha-casozepine. This ingredient was found when researchers speculated that a substance in mother’s milk might be responsible for the state of relaxation newborns experience after nursing. That speculation inspired the discovery of alpha-casozepine, a unique milk-derived protein, which may help promote a sense of relaxation and contentment. Zylkene Equine is the ideal choice for stress-related behavior problems in horses.
  • Provides alpha-casozepine, which may help promote a sense of relaxation and contentment
  • Ideal for helping horses maintain a normal disposition during periods of stress

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Key Ingredients


Supplement Facts

Ingredient Name Amount Per Serving
Ingredient Name Amount Per Pound

Ingredient Details


Weight Recommended Amount Loading Amount

How the Ingredients Work

Supporting Success


The reviews provided on this website represent the experience of the individual posting the review. We do not adopt, edit, or endorse any of the submissions posted within the reviews section. Rather, the reviews are part of an online community of animal owners that desire to share their particular experience with other individuals. These reviews are not a substitute for discussing the health of your animal with a veterinarian.

SmartPak customers are some of the most conscientious animal owners around. We encourage you to share your experience with the products we sell to help fellow customers to make informed choices for their animals. We do not edit these reviews in any way - they are direct customer-to-customer communication. We do monitor reviews for positive and negative feedback, and use this feedback to improve our selection as well as sharing feedback with product manufacturers to help them improve their products. Please note that we recommend consulting your vet with serious health issues.

Zylkene® Equine Powder is rated 4.2 out of 5 by 10.
Rated 5 out of 5 by from fixed her gate sour issue really helped my mare who is gate/ buddy  sour at shows
Date published: 2024-05-22
Rated 5 out of 5 by from Seemed to work I used this to help my mare, who was recovering from an injury, transition from stall rest to being in a paddock by herself. She kept trying to run and buck whenever out of the stall, which could have caused reinjury, but she was much calmer with this and therefore able to continue to heal while getting to go outside and to get light exercise. It seemed expensive but worth it, and I was glad it is made from natural ingredients.
Date published: 2023-04-06
Rated 5 out of 5 by from Absolute Game Changer! I bought this om the recommendation of trainer as my OTTB was in straight up winter mode. Spicy, spooky and everything in between. After a full vetting to ensure nothing medically was going on we gave it a try. He is relaxed, focused and content. This is a real game changer!! Pricey but worth it!
Date published: 2023-02-26
Rated 5 out of 5 by from So thankful for this product I bought this for my move from CA to CO with my gelding who is typically very anxious in the trailer. The last time I trailered him he was calling out, drenched in sweat, and extremely anxious the entire ride. My vet recommended this product and wow I was amazed at how calm my horse was during our move. No sweat, no thrashing, only called out one or two times leaving the property. He was very calm and relaxed just eating his hay. Also loved that he showed no signs of sedation, still bright and alert. I don’t know if it was 100% due to this product but I did not change anything else from our last trailer ride, and he showed the same demeanor both days of our trip. Worth every penny to me.
Date published: 2020-08-24
Rated 5 out of 5 by from Excellent Product! I have used this product when I take my horse to shows and it has made a significant improvement in reducing his anxiety and stress and helping him stay calm in a new environment!
Date published: 2020-07-18
Rated 1 out of 5 by from No change in horse’s behavior Sadly, I saw no change in my horse’s behavior on this product.
Date published: 2020-03-02
Rated 2 out of 5 by from Almost thru my box and have seen no difference in the show ring in my horse.....cant say I would recommend and at $150 wont be ordering again :(
Date published: 2019-07-03
Rated 5 out of 5 by from Foxhunting game-changer I purchased this to help my young horses push through training setbacks and it helped them to focus and not trigger a fight or flight response. However, I also just tried it with my hunt mount and found that it made a huge difference in her during the first 10 minutes after casting the hounds and throughout the hunt. I gave it to her the night before and the morning of the hunt. She was not nearly as reactive to being in large groups with all sorts of horses (some flashy and some crazy). Where she use to be constantly moving at water holes and tack checks, with the Zylkene she stood quietly and was happy for the little breaks. It is pricey, but I feel the results are far better than Ace for my mare.
Date published: 2018-11-11
Rated 4 out of 5 by from Worked for my horse I tried this supplement with my Arab gelding who gets a small amount of anxiety. At first I was not sure as too many variables were at play. I eliminated most of the variables and found that for my gelding, it worked--well--maybe too well. Worth a try but for me, the supplement is too expensive to continue to buy (not SP fault--that is the MSRP on it).
Date published: 2018-04-06
Rated 5 out of 5 by from Totally impressed with this product. It has a definite relaxing/calming effect with NO drowsiness. Compared to any other calming product with magnesium, calming herbs etc, it is no comparison. It really works and if you need something really effective it is worth the $$. I have tried on both mares and geldings with success. A friend of mine had a lot of success with her stallion on Zyklene also!
Date published: 2018-03-24
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